Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 17/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599538 | 0.85 | PTGER1 (0.46) | PTGER1CYP2C9MTNR1AMTNR1BCCR5 | |
| SCHEMBL1355002 | 0.77 | PTGDR2 (0.52) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL2599539 | 0.74 | PTGER1 (0.45) | PTGER1CYP2C9CCR5 | |
| SCHEMBL11297454 | 0.74 | PTGER1 (0.45) | PTGER1CYP2C9CCR5 | |
| SCHEMBL1783946 | 0.73 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL27490007 | 0.73 | CCR5 (0.45) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL9219612 | 0.73 | CHRM2 (0.43) | PTGER1CCR5 | |
| SCHEMBL11301144 | 0.72 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL27507227 | 0.72 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL11297633 | 0.72 | PTGDR2 (0.63) | PTGER1PTGDR2CYP2C9CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145019-A1 | IMPROVED PROCESS FOR DIPHENYLPROPYLAMINE DERIVATIVES | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |