Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.51 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.49 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794249 | 0.86 | PTGER1 (0.59) | PTGER1LTA4HEPHX2PTGER4PTGER3 | |
| SCHEMBL11297633 | 0.85 | PTGDR2 (0.63) | PTGDR2ALDH1A1PTGER1USP28USP25 | |
| SCHEMBL4837693 | 0.85 | PTGDR2 (0.52) | PTGDR2PTGER1LTA4HEPHX2PTGER4 | |
| SCHEMBL1783946 | 0.84 | PTGER1 (0.61) | PTGDR2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27490007 | 0.82 | CCR5 (0.45) | PTGDR2ALDH1A1PTGER1PTGER4PTGER3 | |
| SCHEMBL11301144 | 0.81 | PTGER1 (0.52) | PTGDR2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL17049367 | 0.78 | CCR5 (0.56) | PTGDR2ALDH1A1PTGER1USP28USP25 | |
| SCHEMBL9221452 | 0.77 | FFAR1 (0.48) | PTGER1LTA4HEPHX2PTGER4PTGER3 | |
| SCHEMBL5690733 | 0.77 | PTGER1 (0.53) | PTGDR2ALDH1A1PTGER1USP28USP25 | |
| SCHEMBL2599525 | 0.77 | PTGER1 (0.44) | PTGDR2PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098560-A2 | PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST | MSN LABORATORIES LIMITED (IN) | 2012-07-26 | — | — | WO | claimed |
| WO-2012098560-A2 | PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST | MSN LABORATORIES LIMITED (IN) | 2012-07-26 | — | — | WO | disclosed |
| WO-2011141932-A2 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | INTAS PHARMACEUTICALS LIMITED (IN) | 2011-11-17 | — | — | WO | disclosed |
| US-20110282094-A1 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | INTAS PHARMACEUTICALS LIMITED (IN) | 2011-11-17 | — | — | US | disclosed |
| US-20110171274-A1 | Fesoterodine Substantially Free of Dehydroxy Impurity | ACTAVIS GROUP PTC EHF (IS) | 2011-07-14 | — | — | US | disclosed |
| EP-2323967-A2 | FESOTERODINE COMPRISING A REDUCED AMOUNT OF DEHYDROXYFESOTERODINE | Actavis Group PTC EHF (IS) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010010464-A2 | FESOTERODINE SUBSTANTIALLY FREE OF DEHYDROXY IMPURITY | ACTAVIS GROUP PTC EHF (IS) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282094-A1 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | HPD, COMT, PNMT | PTGDR2 3404/4885ALDH1A1 257/4885PTGER1 2634/4885 |
| US-20110171274-A1 | Fesoterodine Substantially Free of Dehydroxy Impurity | HSD17B7, CYP17A1, CYP21A2 | PTGDR2 2787/4885ALDH1A1 609/4885PTGER1 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.