Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029989 | 0.77 | ADRA2A (0.37) | ADRA2A | |
| SCHEMBL2635508 | 0.72 | TRPA1 (0.39) | — | |
| SCHEMBL1649469 | 0.70 | TRPA1 (0.50) | — | |
| SCHEMBL30403098 | 0.70 | CA2 (0.36) | — | |
| SCHEMBL224636 | 0.67 | TRPA1 (0.42) | SYK | |
| Ammonia Solution, Strong SCHEMBL28509301 | 0.65 | TRPA1 (0.41) | SYK | |
| Hydrochloric Acid SCHEMBL7159867 | 0.65 | TRPA1 (0.41) | SYK | |
| SCHEMBL30794527 | 0.65 | — | — | |
| SCHEMBL8191555 | 0.63 | CA2 (0.40) | ADRA2ACYP19A1TERT | |
| SCHEMBL16430044 | 0.63 | CA12 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571872-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011144578-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |