SCHEMBL25997230

SCHEMBL25997230

CCCCN(CCCC(=O)O)C(=O)C(CNC(=O)C1=C/C=C\C=C/C=C\1)NC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 6/20 0.37
▸ TDP1 Q9NUW8 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ CCKAR P32238 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23419154 0.89 CCKBR (0.30) CCKBR
SCHEMBL26385373 0.78 CCKBR (0.33) CCKBRTDP1LMNAHSD17B10CCKAR
SCHEMBL23453249 0.78 CCKBR (0.31) CCKBRTDP1LMNAHSD17B10
SCHEMBL26050320 0.77 ITGAV (0.34) —
SCHEMBL25997626 0.77 CCKBR (0.31) CCKBRTDP1LMNAHSD17B10
SCHEMBL23419445 0.69 POLB (0.32) —
SCHEMBL23419219 0.69 FOLH1 (0.41) —
SCHEMBL24548543 0.66 MAPT (0.33) —
SCHEMBL26383895 0.66 CCKBR (0.31) CCKBR
SCHEMBL24529726 0.66 CASR (0.35) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12031178-B2 Cyclooctatetraene containing dyes and compositions ILLUMINA CAMBRIDGE LIMITED (GB) 2024-07-09 — — US disclosed
US-20230314322-A1 SYSTEMS AND METHODS OF SEQUENCING POLYNUCLEOTIDES ILLUMINA, INC. 2023-10-05 — — US disclosed
US-20230313292-A1 CHROMENOQUINOLINE DYES AND USES IN SEQUENCING ILLUMINA, INC. 2023-10-05 — — US disclosed
US-20230265503-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
US-20230265502-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
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