SCHEMBL23453249

SCHEMBL23453249

CNC(CNC(=O)C1=C/C=C\C=C/C=C\1)C(=O)N(CCCC(=O)O)CCCS(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 4/20 0.31
▸ TDP1 Q9NUW8 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25997626 0.91 CCKBR (0.31) CCKBRTDP1LMNAHSD17B10
SCHEMBL26385373 0.91 CCKBR (0.33) CCKBRTDP1LMNAHSD17B10
SCHEMBL23419154 0.90 CCKBR (0.30) CCKBR
SCHEMBL25997230 0.78 CCKBR (0.37) CCKBRTDP1LMNAHSD17B10
SCHEMBL26383895 0.77 CCKBR (0.31) CCKBR
SCHEMBL24529726 0.72 CASR (0.35) HSD17B10
SCHEMBL23453251 0.66 KDM4A (0.35) —
SCHEMBL23453248 0.65 LTA4H (0.33) —
SCHEMBL25438806 0.65 SMN1; SMN2 (0.35) —
SCHEMBL23419617 0.64 ITGAV (0.33) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024003087-A1 FLUORESCENT DYES CONTAINING FUSED TETRACYCLIC BIS-BORON HETEROCYCLE AND USES IN SEQUENCING ILLUMINA, INC. (US) 2024-01-04 — — WO disclosed
WO-2023186819-A1 CHROMENOQUINOLINE DYES AND USES IN SEQUENCING ILLUMINA CAMBRIDGE LIMITED (GB) 2023-10-05 — — WO disclosed
WO-2022136402-A1 METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-30 — — WO disclosed
WO-2022129930-A1 ALKYLPYRIDINIUM COUMARIN DYES AND USES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-23 — — WO disclosed
WO-2022129437-A1 LONG STOKES SHIFT CHROMENOQUINOLINE DYES AND USES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-23 — — WO disclosed
WO-2021104845-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-06-03 — — WO disclosed
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