SCHEMBL23419154

SCHEMBL23419154

CC(C)(C)NC(CNC(=O)C1=C/C=C\C=C/C=C\1)C(=O)N(CCCC(=O)O)CCCS(=O)(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23453249 0.90 CCKBR (0.31) CCKBR
SCHEMBL25997626 0.89 CCKBR (0.31) CCKBR
SCHEMBL25997230 0.89 CCKBR (0.37) CCKBR
SCHEMBL26385373 0.88 CCKBR (0.33) CCKBR
SCHEMBL26383895 0.76 CCKBR (0.31) CCKBR
SCHEMBL26050320 0.74 ITGAV (0.34) —
SCHEMBL23419219 0.68 FOLH1 (0.41) —
SCHEMBL23419445 0.66 POLB (0.32) —
SCHEMBL23419424 0.65 OPRK1 (0.33) —
SCHEMBL23453248 0.63 LTA4H (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12031178-B2 Cyclooctatetraene containing dyes and compositions ILLUMINA CAMBRIDGE LIMITED (GB) 2024-07-09 — — US disclosed
US-20230313292-A1 CHROMENOQUINOLINE DYES AND USES IN SEQUENCING ILLUMINA, INC. 2023-10-05 — — US disclosed
US-20230265503-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
US-20230265502-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
US-20220195517-A1 LONG STOKES SHIFT CHROMENOQUINOLINE DYES AND USES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-23 — — US disclosed
US-20220195518-A1 METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-23 — — US disclosed
US-20220195196-A1 ALKYLPYRIDINIUM COUMARIN DYES AND USES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-23 — — US disclosed
US-20220033900-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-02-03 — — US disclosed
US-20210155983-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-05-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220195517-A1 LONG STOKES SHIFT CHROMENOQUINOLINE DYES AND USES IN SEQUENCING APPLICATIONS CHD1L, SYNCRIP, CHD4 CCKBR 1586/4885
US-20220033900-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS FBL, DUT, PHAX CCKBR 2373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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