Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153658 | 0.80 | HSD17B10 (0.65) | APEX1TP53 | |
| SCHEMBL19019393 | 0.78 | TP53 (0.69) | TSHRAPEX1TP53 | |
| SCHEMBL10575419 | 0.78 | LMNA (0.59) | TSHRAPEX1TP53 | |
| SCHEMBL4770587 | 0.78 | TSHR (0.68) | TSHRAPEX1 | |
| SCHEMBL7276010 | 0.77 | TSHR (0.66) | TSHRAPEX1NPSR1 | |
| SCHEMBL687878 | 0.77 | TSHR (0.79) | TSHRAPEX1 | |
| SCHEMBL12781878 | 0.75 | MEN1 (0.70) | TSHRHTTNPSR1 | |
| SCHEMBL23169217 | 0.74 | KMT2A (0.58) | TSHRHTTTP53 | |
| SCHEMBL10344941 | 0.74 | TSHR (0.56) | TSHRAPEX1TP53 | |
| SCHEMBL10883879 | 0.74 | APEX1 (0.66) | TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011144659-A1 | SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS | ALZCHEM TROSTBERG GMBH (DE) | 2011-11-24 | — | — | WO | disclosed |