SCHEMBL2599768

SCHEMBL2599768

CN(C)C(=O)NN=C1CCCC1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.49
RAB9A P51151 1/20 0.49
RXFP1 Q9HBX9 1/20 0.47
POLB P06746 2/20 0.46
RECQL P46063 1/20 0.46
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2599771 0.98 KDM4E (0.51) KDM4ERAB9ARXFP1POLBRECQL
SCHEMBL2599775 0.79 RXFP1 (0.47) KDM4ERAB9ARXFP1POLBRECQL
SCHEMBL80049 0.73 KDM4E (0.71) KDM4ERAB9ARXFP1POLBALDH1A1
SCHEMBL7354510 0.73 KDM4E (0.50) KDM4ERAB9ARXFP1POLBRECQL
SCHEMBL9356593 0.71 KDM4E (0.48) KDM4ERAB9ARXFP1POLBRECQL
SCHEMBL7351663 0.71 KDM4E (0.53) KDM4ERAB9ARXFP1POLBALDH1A1
SCHEMBL9356896 0.70 KDM4E (0.52) KDM4ERAB9ARXFP1POLBALDH1A1
SCHEMBL7345401 0.69
SCHEMBL573354 0.67 ALDH1A1 (0.63) KDM4ERAB9ARXFP1POLBRECQL
SCHEMBL17231392 0.67 KDM4E (0.68) KDM4ERAB9ARXFP1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780410-B1 ALKYL OR DIALKYL-SEMICARBAZONES AS A HARDENERS FOR EPOXY RESIN ALZCHEM AG (DE) 2017-09-06 EP claimed
US-9499684-B2 Alkyl or dialkyl-semicarbazone as a hardener for epoxy resin ALZCHEM AG (DE) 2016-11-22 US claimed
US-20140308863-A1 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2014-10-16 US claimed
EP-2780410-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN AlzChem AG (DE) 2014-09-24 EP claimed
WO-2013072354-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2013-05-23 WO claimed
US-20130079488-A1 Semicarbazones as Accelerators for Curing Epoxy Resins ALZCHEM AG (DE) 2013-03-28 US claimed
EP-2571917-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS AlzChem AG (DE) 2013-03-27 EP claimed
WO-2011144659-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2011-11-24 WO claimed
EP-2780410-B1 ALKYL OR DIALKYL-SEMICARBAZONES AS A HARDENERS FOR EPOXY RESIN ALZCHEM AG (DE) 2017-09-06 EP disclosed
EP-2571917-B1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS ALZCHEM AG (DE) 2016-12-07 EP disclosed
US-9499684-B2 Alkyl or dialkyl-semicarbazone as a hardener for epoxy resin ALZCHEM AG (DE) 2016-11-22 US disclosed
US-9403976-B2 Semicarbazones as accelerators for curing epoxy resins ALZCHEM AG (DE) 2016-08-02 US disclosed
US-20160083575-A1 Semicarbazones as accelerators for curing epoxy resins ALZCHEM AG (DE) 2016-03-24 US disclosed
WO-2015113930-A1 LIQUID CURING COMPOSITION FOR CURING POLYMER RESINS (I) ALZCHEM AG (DE) 2015-08-06 WO disclosed
US-20140308863-A1 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2014-10-16 US disclosed
EP-2780410-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN AlzChem AG (DE) 2014-09-24 EP disclosed
WO-2013072354-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2013-05-23 WO disclosed
US-20130079488-A1 Semicarbazones as Accelerators for Curing Epoxy Resins ALZCHEM AG (DE) 2013-03-28 US disclosed
EP-2571917-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS AlzChem AG (DE) 2013-03-27 EP disclosed
WO-2011144659-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2011-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130079488-A1 Semicarbazones as Accelerators for Curing Epoxy Resins EP300, HDAC2, HDAC1 KDM4E 98/4885RAB9A 4049/4885RXFP1 1911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.