SCHEMBL26000676

SCHEMBL26000676

CC(C)(C)OC(=O)NCC1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 13/20 0.68
LMNA P02545 6/20 0.61
MAPT P10636 6/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
CYP3A4 P08684 4/20 0.61
MAPK1 P28482 4/20 0.61
TP53 P04637 3/20 0.61
RAD52 P43351 3/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP1A2 P05177 2/20 0.61
ABCB1 P08183 2/20 0.61
HTR1A P08908 2/20 0.61
ADRA2A P08913 2/20 0.61
ADORA3 P0DMS8 2/20 0.61
CYP2D6 P10635 2/20 0.61
CHRM1 P11229 2/20 0.61
DRD2 P14416 2/20 0.61
ADRA2B P18089 2/20 0.61
ADRA2C P18825 2/20 0.61
NFKB1 P19838 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30057046 1.00 FPR2 (0.68) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL4274255 0.91 FPR2 (0.61) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL560221 0.88 KIF11 (0.68) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL23039384 0.88 FPR2 (0.74) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL21445237 0.87 FPR2 (0.78) FPR2MEN1KMT2A
SCHEMBL30058599 0.87 FPR2 (0.78) FPR2MEN1KMT2A
SCHEMBL560237 0.87 FPR2 (0.67) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL4275410 0.83 RAD52 (0.51) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL1070098 0.82 FPR2 (0.62) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL21445213 0.82 FPR2 (0.71) FPR2LMNAMAPTSMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885LMNA 546/4885MAPT 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.