Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.40 |
| ▸ | CBX7 | O95931 | 2/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600350 | 0.95 | CDYL (0.39) | NPY5RUBE2MDCUN1D1CDYLCDY1; CDY1B | |
| SCHEMBL2600343 | 0.88 | MAPT (0.46) | NPY5RUBE2MDCUN1D1ALDH1A1CCR5 | |
| SCHEMBL2600358 | 0.88 | SMN1; SMN2 (0.39) | NPY5RCDYLCDY1; CDY1BCBX7CDYL2 | |
| SCHEMBL2600348 | 0.87 | NPY5R (0.43) | NPY5RALDH1A1SMN1; SMN2CCR5EPHX2 | |
| SCHEMBL2600345 | 0.86 | CCR5 (0.39) | NPY5RALDH1A1SMN1; SMN2CCR5 | |
| SCHEMBL2600330 | 0.86 | NPY5R (0.45) | NPY5RALDH1A1SMN1; SMN2CCR5HTT | |
| SCHEMBL2600351 | 0.86 | RAB9A (0.39) | NPY5RALDH1A1SMN1; SMN2CCR5 | |
| SCHEMBL2600349 | 0.85 | ABL1 (0.40) | NPY5RCCR5HTT | |
| SCHEMBL2600353 | 0.85 | ABL1 (0.40) | CCR5HTT | |
| SCHEMBL2600308 | 0.84 | ALDH1A1 (0.40) | NPY5RALDH1A1SMN1; SMN2CCR5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372833-B2 | Urea derivative | SHIONOGI & CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372833-B2 | Urea derivative | SHIONOGI & CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-20120095231-A1 | UREA DERIVATIVE | YANO TOSHISADA (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120095231-A1 | UREA DERIVATIVE | YANO TOSHISADA (JP) | 2012-04-19 | — | — | US | disclosed |
| US-8088777-B2 | Urea derivative | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-8088777-B2 | Urea derivative | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20090203712-A1 | Urea Derivative | SHIONOGI &CO., LTD. | 2009-08-13 | — | — | US | disclosed |
| US-20090203712-A1 | Urea Derivative | SHIONOGI &CO., LTD. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095231-A1 | UREA DERIVATIVE | NPY5R, NPY1R, NPY2R | NPY5R 1/4885UBE2M 3194/4885DCUN1D1 3899/4885 |
| US-20090203712-A1 | Urea Derivative | NPY5R, NPY1R, NPY2R | NPY5R 1/4885UBE2M 3195/4885DCUN1D1 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.