SCHEMBL2600447

SCHEMBL2600447

c1ccc(N2CCc3ccccc3C2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EED O75530 2/20 0.72
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
GRIN2B Q13224 7/20 0.55
GRIN2D O15399 6/20 0.55
GRIN3B O60391 6/20 0.55
GRIN1 Q05586 6/20 0.55
GRIN2A Q12879 6/20 0.55
GRIN2C Q14957 6/20 0.55
GRIN3A Q8TCU5 6/20 0.55
MAOA P21397 2/20 0.54
MAOB P27338 2/20 0.54
GAA P10253 1/20 0.50
NPC1 O15118 1/20 0.49
CYP1A2 P05177 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10535845 0.98 EED (0.70) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL8494183 0.88 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL10535865 0.84 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL29977823 0.84 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL29836510 0.84 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL10534867 0.84 MEN1 (0.75) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL6441852 0.84 EED (1.00) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL702928 0.84 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL10534823 0.84 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D
SCHEMBL30296914 0.84 EED (0.64) EEDMEN1KMT2AGRIN2BGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119753868-A Preparation method and application of dual fluorescence resonance energy transfer light capturing nanofiber 山东中康国创先进印染技术研究院有限公司 2025-04-04 CN claimed
CN-118754851-A Perovskite light application of catalyst 南昌大学 2024-10-11 CN claimed
CN-118719100-A Application of leadless double perovskite catalyst 南昌大学 2024-10-01 CN claimed
CN-117946001-A Method for coupling near infrared photocatalysis 2-benzene-1, 2,3, 4-tetrahydroisoquinoline compound and nucleophile 陕西师范大学 2024-04-30 CN claimed
CN-117447441-A Difluoromethyl reagent and preparation method and application thereof 深圳大学 2024-01-26 CN claimed
CN-116041319-B Preparation method of indolyl tetrahydroisoquinoline derivative 江苏中利集团股份有限公司 2023-08-25 CN claimed
CN-114669319-B Nanometer cobaltosic oxide-carbon nitrogen composite catalyst and preparation method and application thereof 南京航空航天大学 2023-06-23 CN claimed
CN-116082233-A Application of hollow prism bimetallic oxide catalyst in cross dehydrogenation coupling reaction 南昌大学 2023-05-09 CN claimed
CN-116041319-A Preparation method of indolyl tetrahydroisoquinoline derivative 江苏中利集团股份有限公司 2023-05-02 CN claimed
US-20230120881-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS University of Hong Kong Versitech Limited (CN) 2023-04-20 US claimed
CN-111285804-A Method for synthesizing thioamide compound 广州中医药大学(广州中医药研究院) 2020-06-16 CN claimed
CN-111116677-A Preparation method and application of metal-organic framework structure compound with chiral pore structure 大连理工大学 2020-05-08 CN claimed
CN-109251173-A A kind of method of hydrotalcite-like materials catalysis tetrahydro isoquinoline derivative oxidative coupling 常州大学 2019-01-22 CN claimed
CN-104447865-B Preparation method of alpha-phosphoramidate compound 四川理工学院 2017-01-11 CN claimed
CN-102627604-B Two class isoquinoline compounds and as the application preparing cancer therapy drug NORTHWEST A & F UNIVERSITY (CN) 2015-12-09 CN claimed
CN-103755588-B A kind of synthetic method of covalent organic frame material and application LANZHOU UNIVERSITY (CN) 2015-09-23 CN claimed
CN-104447865-A Preparation method of alpha-phosphoramidate compound UNIV SICHUAN SCI & ENG 2015-03-25 CN claimed
CN-101759637-B N-aryl-3,4-dihydro-isoquinoline salt and application thereof in preparing acaricidal and antibiotic medicament NORTHWEST A & F UNIVERSITY (CN) 2012-02-01 CN claimed
EP-0025598-B1 THE USE OF 2-PHENYLTETRALIN DERIVATIVES, OR HETEROCYCLIC ANALOGUES, IN MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1984-08-01 EP claimed
EP-0025598-A1 The use of 2-phenyltetralin derivatives, or heterocyclic analogues, in medicine and pharmaceutical compositions containing them THE WELLCOME FOUNDATION LIMITED (GB) 1981-03-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230120881-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS PPOX, AP3M1, AP2M1 EED 2070/4885MEN1 4332/4885KMT2A 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.