Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977823 | 1.00 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12391616 | 0.91 | EED (0.54) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24921338 | 0.89 | EED (0.53) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31432954 | 0.86 | MAPT (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13232537 | 0.86 | MAPT (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24921996 | 0.85 | EED (0.49) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2600447 | 0.84 | EED (0.72) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10534812 | 0.84 | ALDH1A1 (0.76) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL10535845 | 0.82 | EED (0.70) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8494183 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251173-B | Method for catalyzing oxidation coupling of tetrahydroisoquinoline derivatives by hydrotalcite-like material | 常州大学 | 2022-01-25 | — | — | CN | claimed |
| CN-111285804-B | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2022-01-07 | — | — | CN | claimed |
| CN-111285804-A | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | claimed |
| CN-117946001-A | Method for coupling near infrared photocatalysis 2-benzene-1, 2,3, 4-tetrahydroisoquinoline compound and nucleophile | 陕西师范大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-116462683-A | N-condensed ring indole compound and preparation method thereof | 常州大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-113264881-B | Synthetic method of alpha-cyanide | 南昌大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-109251173-B | Method for catalyzing oxidation coupling of tetrahydroisoquinoline derivatives by hydrotalcite-like material | 常州大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-111285804-B | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2022-01-07 | — | — | CN | disclosed |
| CN-113264881-A | Synthetic method of alpha-cyanide | 南昌大学 | 2021-08-17 | — | — | CN | disclosed |
| CN-111285804-A | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | disclosed |
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| CN-103449945-A | Visible light catalysis cross coupling hydrogen releasing method | CHINESE ACAD TECH INST PHYSICS | 2013-12-18 | — | — | CN | disclosed |
| US-8124121-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX, INC. | 2009-04-30 | — | — | US | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
| US-4801593-A | VIRICIDE FOR RHINITIS VIRUS CONTAINING 2-PHENYLTETRALIN DERIVATIVE | BURROUGHS WELLCOME CO. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0025598-B1 | THE USE OF 2-PHENYLTETRALIN DERIVATIVES, OR HETEROCYCLIC ANALOGUES, IN MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-08-01 | — | — | EP | disclosed |
| EP-0025598-A1 | The use of 2-phenyltetralin derivatives, or heterocyclic analogues, in medicine and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | EED 4381/4885GRIN2D 2239/4885GRIN3B 828/4885 |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | EED 4363/4885GRIN2D 2057/4885GRIN3B 758/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | EED 2862/4885GRIN2D 225/4885GRIN3B 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.