Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600447 | 0.88 | EED (0.72) | EEDMEN1KMT2ANPC1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10535845 | 0.86 | EED (0.70) | EEDMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL27723823 | 0.86 | EED (0.81) | EEDMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL6380662 | 0.86 | MEN1 (0.54) | EEDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10534867 | 0.81 | MEN1 (0.75) | EEDMEN1KMT2ANPC1MAPT | |
| SCHEMBL10535865 | 0.81 | EED (0.64) | EEDMEN1KMT2ANPC1MAPT | |
| SCHEMBL29375196 | 0.81 | EED (0.64) | EEDMEN1KMT2AMAPTGRIN2D | |
| SCHEMBL702928 | 0.81 | EED (0.64) | EEDMEN1KMT2AMAPTGRIN2D | |
| SCHEMBL10534823 | 0.81 | EED (0.64) | EEDMEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL30101805 | 0.81 | EED (0.64) | EEDMEN1KMT2AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999024022-A2 | ISOQUINOLINE DERIVATIVES FOR TREATING DISORDERS ASSOCIATED WITH 5HT7 RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-20 | — | — | WO | disclosed |