Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052295 | 0.86 | NPC1 (0.66) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6172144 | 0.86 | NPSR1 (0.67) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6175085 | 0.85 | CA12 (0.62) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24303811 | 0.83 | CA12 (0.56) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29333624 | 0.83 | NPSR1 (0.48) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6052147 | 0.81 | MEN1 (0.53) | CA12CA9RAB9ALMNANPC1 | |
| SCHEMBL29332783 | 0.80 | HTT (0.53) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17980321 | 0.79 | NPC1 (0.49) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14581231 | 0.79 | MAPK1 (0.45) | CA12CA9RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29332803 | 0.78 | RAB9A (0.63) | CA12CA9RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265068-A1 | TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | US | disclosed |
| EP-3999505-A1 | PESTICIDAL PYRAZOLE AND TRIAZOLE DERIVATIVES | BASF SE (DE) | 2022-05-25 | — | — | EP | disclosed |
| CN-114174267-A | Pesticidal pyrazole and triazole derivatives | 巴斯夫欧洲公司 | 2022-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265068-A1 | TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 INHIBITORS AND METHODS OF USE THEREOF | TRPC3, TRPV3, TRPV1 | CA12 3946/4885CA9 4071/4885RAB9A 2801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.