Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25135025 | 0.92 | OPRM1 (0.41) | DRD2SLC6A4HRH2HTR2ADRD3 | |
| SCHEMBL21084744 | 0.91 | DRD2 (0.36) | DRD2SLC6A4HRH2HTR2ADRD3 | |
| SCHEMBL19972626 | 0.91 | HTR2A (0.38) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL30524098 | 0.91 | HTR2A (0.38) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL30524087 | 0.90 | DRD2 (0.35) | DRD2SLC6A4HRH2HTR2ADRD3 | |
| SCHEMBL19972430 | 0.90 | DRD2 (0.35) | DRD2SLC6A4HRH2HTR2ADRD3 | |
| SCHEMBL19972628 | 0.90 | HRH2 (0.37) | DRD2SLC6A4HRH2HTR2ADRD3 | |
| SCHEMBL19972630 | 0.90 | HRH2 (0.37) | DRD2SLC6A4HRH2HTR2ADRD3 | |
| SCHEMBL31001678 | 0.90 | HTR1A (0.37) | DRD2SLC6A4 | |
| SCHEMBL19972525 | 0.90 | HTR1A (0.37) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230627-A2 | INHIBITORS OF THE MENIN-MLL INTERACTION | Vitae Pharmaceuticals, LLC (US) | 2023-08-23 | — | — | EP | disclosed |