Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22878348 | 0.89 | CYP2D6 (0.36) | CCR4SMYD3CYP2D6HRH1KCNH2 | |
| SCHEMBL22878325 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13306227 | 0.82 | — | — | |
| SCHEMBL7580833 | 0.80 | HRH4 (0.34) | CCR4SMYD3 | |
| SCHEMBL20080155 | 0.79 | CYP2D6 (0.35) | SMN1; SMN2CYP2D6HRH1KCNH2 | |
| SCHEMBL25955532 | 0.79 | DRD3 (0.37) | SMN1; SMN2 | |
| SCHEMBL22878130 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2AGTR2 | |
| SCHEMBL9949604 | 0.78 | HRH4 (0.37) | CYP2D6 | |
| SCHEMBL5663844 | 0.76 | SIGMAR1 (0.39) | CCR4SMN1; SMN2SMYD3SLC6A2 | |
| SCHEMBL17743426 | 0.76 | HRH4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |