SCHEMBL2600792

SCHEMBL2600792

O=C(O)COC(=O)COCC(=O)OCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 3/20 0.46
TSHR P16473 1/20 0.41
CTH P32929 1/20 0.41
CBS P35520 1/20 0.41
THPO P40225 1/20 0.41
THRB P10828 1/20 0.39
PTGS1 P23219 1/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 2/20 0.31
USP2 O75604 1/20 0.31
TTR P02766 1/20 0.31
CYP2C9 P11712 1/20 0.31
TBXA2R P21731 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6360573 0.97 PAM (0.45) PAMTSHRCTHCBSTHPO
SCHEMBL12286261 0.88 PAM (0.44) PAMTSHRCTHCBSTHPO
SCHEMBL17672288 0.86 TSHR (0.39) PAMTSHRCTHCBSTHPO
SCHEMBL803309 0.83 PAM (0.39) PAMTSHRCTHCBSTHPO
SCHEMBL9195118 0.79 GAA (0.50) PAMTSHRPTGS1ALOX15LMNA
SCHEMBL10012587 0.79 TSHR (0.47) PAMTSHRCTHCBSTHPO
SCHEMBL8775561 0.79 TDP1 (0.47) PAMTSHRCTHCBSTHPO
SCHEMBL94604 0.79 PAM (0.60) PAMTSHRCTHCBSTHPO
SCHEMBL4323711 0.79 PAM (0.48) PAMTSHRCTHCBSTHPO
SCHEMBL13469586 0.78 PAM (0.48) PAMTSHRCTHCBSTHPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2016-01-28 US disclosed
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2016-01-28 US disclosed
US-9174924-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-11-03 US disclosed
US-9174924-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-11-03 US disclosed
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2015-09-17 US disclosed
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2015-09-17 US disclosed
US-9045396-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-06-02 US disclosed
US-9045396-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-06-02 US disclosed
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2014-06-12 US disclosed
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2014-06-12 US disclosed
US-8026285-B2 Control release of biologically active compounds from multi-armed oligomers BEZWADA BIOMEDICAL, LLC (US) 2011-09-27 US disclosed
US-8026285-B2 Control release of biologically active compounds from multi-armed oligomers BEZWADA BIOMEDICAL, LLC (US) 2011-09-27 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-26 US disclosed
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-26 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885TSHR 4662/4885CTH 199/4885
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 PAM 528/4885TSHR 2565/4885CTH 1558/4885
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS MME, CTSA, ALG1 PAM 587/4885TSHR 3963/4885CTH 2044/4885
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885TSHR 4662/4885CTH 199/4885
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885TSHR 4662/4885CTH 199/4885
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 PAM 22/4885TSHR 4800/4885CTH 4365/4885
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885TSHR 4662/4885CTH 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.