Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873282 | 0.85 | TDP1 (0.61) | TDP1TSHRCYP3A4PKMSMN1; SMN2 | |
| SCHEMBL238623 | 0.84 | — | — | |
| SCHEMBL11829533 | 0.83 | TDP1 (0.56) | TDP1TSHRPTGS1CYP3A4PKM | |
| SCHEMBL8063306 | 0.83 | TDP1 (0.59) | TDP1TSHRCYP3A4PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11313915 | 0.82 | — | — | |
| SCHEMBL2600792 | 0.79 | PAM (0.46) | TDP1PAMTSHRPTGS1CTH | |
| SCHEMBL1471358 | 0.79 | TDP1 (0.51) | TDP1TSHRSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL3430807 | 0.78 | TDP1 (0.63) | TDP1TSHRCYP3A4PKMSMN1; SMN2 | |
| SCHEMBL6360573 | 0.77 | PAM (0.45) | TDP1PAMTSHRPTGS1CTH | |
| SCHEMBL15234311 | 0.76 | ALDH1A1 (0.44) | TDP1PAMTSHRMAPTCTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804430-A1 | SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5656662-A | TREATING OR PREVENTING ATHEROSCLEROTIC DISORDERS, INHIBITING INFLAMMATORY CYTOKINES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1995032194-A1 | SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-11-30 | — | — | WO | disclosed |