Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286302 | 0.97 | PAM (0.57) | PAMCES2DGKAALDH1A1PRSS1 | |
| SCHEMBL16300324 | 0.92 | PAM (0.58) | PAMCES2DGKAALDH1A1PRSS1 | |
| SCHEMBL2600794 | 0.89 | PAM (0.61) | PAMCES2DGKAALDH1A1PRSS1 | |
| SCHEMBL17463468 | 0.84 | PAM (0.63) | PAMDGKAALDH1A1DNM1EPHX2 | |
| SCHEMBL17463465 | 0.83 | PAM (0.68) | PAMDGKAALDH1A1DNM1TSHR | |
| SCHEMBL3438976 | 0.79 | CES2 (0.50) | PAMCES2ALDH1A1PLA2G4BCYP2C19 | |
| SCHEMBL12286261 | 0.78 | PAM (0.44) | PAMCES2GAATSHR | |
| SCHEMBL11837895 | 0.78 | PAM (0.57) | PAMCES2DGKAALDH1A1PRSS1 | |
| SCHEMBL15445502 | 0.78 | PAM (0.47) | PAMDGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL12287044 | 0.77 | PAM (0.51) | PAMCES2DGKAALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130035402-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-07 | — | — | US | disclosed |
| US-8309132-B2 | Bioabsorbable polyesteramides and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2012-11-13 | — | — | US | disclosed |
| US-8163806-B2 | Controlled release of biologically active compounds from multi-armed oligomers | BEZWADA BIOMEDICAL, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20120010284-A1 | CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS | BEZWADA BIOMEDICAL, LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-8026285-B2 | Control release of biologically active compounds from multi-armed oligomers | BEZWADA BIOMEDICAL, LLC (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2009-11-19 | — | — | US | disclosed |
| US-20090076174-A1 | CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS | BEZWADA BIOMEDICAL, LLC (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076174-A1 | CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS | MME, CTSA, ALG1 | PAM 587/4885CES2 847/4885DGKA 3158/4885 |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | PAICS, UROD, PUF60 | PAM 22/4885CES2 2919/4885DGKA 926/4885 |
| US-20120010284-A1 | CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS | MME, AADAC, LGMN | PAM 534/4885CES2 828/4885DGKA 3147/4885 |
| US-20130035402-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | PAICS, UROD, PUF60 | PAM 22/4885CES2 2919/4885DGKA 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.