SCHEMBL26009

SCHEMBL26009

N#COc1cccc(OC#N)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
GFER P55789 1/20 0.36
NLRP1 Q9C000 1/20 0.36
NOD2 Q9HC29 1/20 0.36
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19808928 0.95 KMT2A (0.38) KMT2AMEN1PDE4APDE4BPDE4C
SCHEMBL11032757 0.93 MEN1 (0.46) KMT2AMEN1ALDH1A1SMN1; SMN2MITF
SCHEMBL11849487 0.89 ACHE (0.50) PDE4APDE4BPDE4CPDE4DALDH1A1
SCHEMBL2588766 0.89 ALDH1A1 (0.54) KMT2AMEN1ALDH1A1SMN1; SMN2MITF
SCHEMBL1191136 0.87 TSHR (0.50) KMT2AMEN1ALDH1A1SMN1; SMN2MITF
SCHEMBL15436143 0.85 MEN1 (0.31) KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL3139018 0.84 NFE2L2 (0.39) ALDH1A1MAPTACHE
SCHEMBL11651636 0.84 CYP3A4 (0.52) ALDH1A1CA1CA2CA9LMNA
SCHEMBL4179729 0.84 ACHE (0.56) KMT2AALDH1A1GAAMAPTLMNA
SCHEMBL3420413 0.84 MEN1 (0.34) KMT2AMEN1ALDH1A1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1043 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474533-B Cyanate ester foam plastic 中国科学院化学研究所 2020-09-04 CN claimed
CN-107502277-B High-toughness cyanate ester adhesive 中国科学院化学研究所 2020-02-21 CN claimed
CN-107474534-B Preparation method of cyanate foamed plastic 中国科学院化学研究所 2020-02-21 CN claimed
CN-107400496-B Silazane hybrid cyanate adhesive 中国科学院化学研究所 2020-02-18 CN claimed
CN-107400235-B Cyanate hybridized polymer and cyanate composite material 中国科学院化学研究所 2019-10-11 CN claimed
US-20180127537-A1 RESINS AND COMPOSITIONS FOR HIGH TEMPERATURE APPLICATIONS HENKEL AG & CO. KGAA (DE) 2018-05-10 US claimed
CN-107400496-A A kind of silazane hydridization cyanate ester adhesive 中国科学院化学研究所 2017-11-28 CN claimed
WO-2016099922-A2 RESINS AND COMPOSITIONS FOR HIGH TEMPERATURE APPLICATIONS Henkel IP & Holding GmbH (DE) 2016-06-23 WO claimed
EP-1979397-B1 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RES GROUP INC (US) 2011-09-07 EP claimed
US-20100140542-A1 BENZOXAZINE CONTAINING COMPOSITIONS OF MATTER AND CURABLE COMPOSITIONS MADE THEREWITH HENKEL CORPORATION (US) 2010-06-10 US claimed
EP-1265947-A1 QUICK-SETTING MIXTURES AND KITS WITH POLYFUNCTIONAL CYANATES AND AMINES, THE THERMOSETS PRODUCED THEREFROM AND METHODS FOR THE PRODUCTION THEREOF FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2002-12-18 EP claimed
US-20020107308-A1 Curable epoxy resin compositions and the cured residues thereof CITIBANK, N.A., AS COLLATERAL AGENT 2002-08-08 US claimed
US-20020058778-A1 Toughened thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-05-16 US claimed
US-6342577-B1 Thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-01-29 US claimed
WO-2001068741-A1 QUICK-SETTING MIXTURES AND KITS WITH POLYFUNCTIONAL CYANATES AND AMINES, THE THERMOSETS PRODUCED THEREFROM AND METHODS FOR THE PRODUCTION THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2001-09-20 WO claimed
JP-2001506313-A 2001-05-15 JP claimed
EP-0929592-A4 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS LOCTITE CORP (US) 2000-09-13 EP claimed
EP-0929592-A1 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS LOCTITE CORPORATION (US) 1999-07-21 EP claimed
WO-1999005196-A1 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS LOCTITE CORPORATION (US) 1999-02-04 WO claimed
US-5403896-A Crosslinking to form cyanurate groups or polymers ALLIEDSIGNAL INC. (US) 1995-04-04 US claimed