Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15748014 | 0.90 | HPGDS (0.60) | HPGDSGABRA5P4HTMTP53BAZ2B | |
| SCHEMBL14082207 | 0.80 | TRPV1 (0.58) | HPGDSGABRA5PDE2APDE10ARIPK1 | |
| SCHEMBL15748102 | 0.80 | HPGDS (0.48) | HPGDSGABRA5BAZ2BRIPK1KMT2A | |
| SCHEMBL27001722 | 0.78 | LDHA (0.62) | HPGDSGABRA5P4HTMTP53KDM4E | |
| SCHEMBL21553939 | 0.78 | SMN1; SMN2 (0.49) | HPGDSKMT2AKDM4EHTTL3MBTL1 | |
| SCHEMBL24268560 | 0.76 | TP53 (0.46) | HPGDSP4HTMTP53KMT2ATRPM8 | |
| SCHEMBL13886161 | 0.76 | CDK8 (0.56) | HPGDSGABRA5PDE2APDE10ARIPK1 | |
| SCHEMBL14355073 | 0.76 | HPGDS (0.55) | HPGDSGABRA5PDE2ATP53BAZ2B | |
| SCHEMBL25912773 | 0.76 | P4HTM (0.54) | HPGDSGABRA5P4HTMTP53BAZ2B | |
| SCHEMBL15133134 | 0.75 | HPGDS (0.48) | HPGDSP4HTMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732001-B2 | Methods of incorporating an amino acid comprising a BCN group into a polypeptide using an orthogonal codon encoding it and an orthogonal pylrs synthase | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11732001-B2 | Methods of incorporating an amino acid comprising a BCN group into a polypeptide using an orthogonal codon encoding it and an orthogonal pylrs synthase | COASY, BCAT1, FARSA | HPGDS 957/4885GABRA5 1275/4885P4HTM 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.