SCHEMBL2601562

SCHEMBL2601562

CC(C)(C)c1ccc2c(c1)c1c3ccc4ccc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)c5ccc(cc1n2-c1ccccc1)c3c45

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ TP53 P04637 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CDK1 P06493 1/20 0.30
▸ CDK4 P11802 1/20 0.30
▸ CCNB1 P14635 1/20 0.30
▸ CCND1 P24385 1/20 0.30
▸ CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14460349 0.89 ALDH1A1 (0.32) ALDH1A1MAPTMAPK1NPSR1
SCHEMBL10034226 0.88 JAK2 (0.32) —
SCHEMBL2601557 0.88 TDP2 (0.33) —
SCHEMBL10034225 0.87 KDM4E (0.37) —
SCHEMBL2601549 0.87 KDM4E (0.37) —
SCHEMBL10034219 0.87 JAK2 (0.31) —
SCHEMBL10034222 0.87 JAK2 (0.31) —
SCHEMBL2601551 0.86 KDM4E (0.32) —
SCHEMBL2601475 0.86 KDM4E (0.38) —
SCHEMBL10034160 0.86 KDM4E (0.38) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448035-B1 Organic light-emitting device SAMSUNG DISPLAY CO LTD (KR) 2014-06-11 — — EP disclosed
US-8546793-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-10-01 — — US disclosed
US-8546793-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-10-01 — — US disclosed
EP-2448035-A2 Organic light-emitting device Samsung Mobile Display Co., Ltd. (KR) 2012-05-02 — — EP disclosed
US-20120097925-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 — — US disclosed
US-20120097925-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120097925-A1 ORGANIC LIGHT-EMITTING DEVICE AR, NR2E3, CRY1 ALDH1A1 74/4885MAPT 1507/4885MAPK1 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback