SCHEMBL2601598

SCHEMBL2601598

Brc1ccc2ccc3c4c(ccc1c24)cc1c3c2cc(N(c3ccncc3)c3ccncc3)ccc2n1-c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ JAK2 O60674 1/20 0.30
▸ JAK3 P52333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14460552 0.87 — —
SCHEMBL2601482 0.86 — —
SCHEMBL14330617 0.82 REN (0.36) —
SCHEMBL10034189 0.80 KDM4E (0.34) —
SCHEMBL2601511 0.80 KDM4E (0.34) —
SCHEMBL14330623 0.79 CDK4 (0.37) —
SCHEMBL10034238 0.79 L3MBTL1 (0.46) JAK2JAK3
SCHEMBL2601571 0.79 L3MBTL1 (0.46) JAK2JAK3
SCHEMBL14329632 0.77 TOP2A (0.33) —
SCHEMBL15803148 0.77 KDM4E (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546793-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-10-01 — — US disclosed
US-8546793-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-10-01 — — US disclosed
EP-2448035-A2 Organic light-emitting device Samsung Mobile Display Co., Ltd. (KR) 2012-05-02 — — EP disclosed
US-20120097925-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 — — US disclosed
US-20120097925-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120097925-A1 ORGANIC LIGHT-EMITTING DEVICE AR, NR2E3, CRY1 JAK2 2463/4885JAK3 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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