Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12102096 | 0.79 | PDE5A (0.47) | PDE5APARP1 | |
| SCHEMBL13833239 | 0.79 | KDM4E (0.49) | PDE5AMEN1KMT2A | |
| SCHEMBL1623385 | 0.75 | PDE5A (0.44) | PDE5AHCAR2PARP1 | |
| SCHEMBL26018347 | 0.74 | KDM4C (0.35) | HCAR2PARP1MEN1KMT2A | |
| SCHEMBL3663889 | 0.73 | PDE5A (0.41) | PDE5AHCAR2 | |
| SCHEMBL7787137 | 0.73 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL26017631 | 0.71 | HCAR2 (0.59) | HCAR2PARP1 | |
| SCHEMBL29774108 | 0.69 | PDE5A (0.37) | PDE5AMEN1KMT2A | |
| SCHEMBL30593810 | 0.68 | SMN1; SMN2 (0.48) | PDE5APARP1 | |
| SCHEMBL7017053 | 0.68 | SMN1; SMN2 (0.48) | PDE5APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |