Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277595 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL5632 | 0.75 | NUDT1 (0.50) | METAP2METAP1NPY5R | |
| SCHEMBL31064848 | 0.75 | SMN1; SMN2 (0.52) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL30388675 | 0.75 | NUDT1 (0.50) | METAP2METAP1NPY5R | |
| SCHEMBL375955 | 0.75 | SMN1; SMN2 (0.52) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL2968462 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL277596 | 0.75 | METAP2 (0.51) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL9936013 | 0.75 | METAP2 (0.44) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL9356684 | 0.75 | METAP2 (0.44) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL18757950 | 0.73 | METAP2 (0.46) | METAP2METAP1NPY5RENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773344-B | Method for synthesizing 2/6-iodopurine derivative through visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2023-03-14 | — | — | CN | disclosed |
| CN-114773344-A | Method for synthesizing 2/6-iodopurine derivative by visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2022-07-22 | — | — | CN | disclosed |
| CN-101646657-B | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL CO JP | 2012-08-08 | — | — | CN | disclosed |
| CN-101646657-A | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL CO JP | 2010-02-10 | — | — | CN | disclosed |
| JP-2001072680-A | NEW METHOD FOR PRODUCING PURINE IODIDE DERIVATIVE | EISAI CO LTD | 2001-03-21 | — | — | JP | disclosed |
| JP-2001072680-A | NEW METHOD FOR PRODUCING PURINE IODIDE DERIVATIVE | EISAI CO LTD | 2001-03-21 | — | — | JP | disclosed |
| EP-0479640-A2 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0477454-A1 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| CN-1036578-A | NOVEL FLUOROPHOSPHONATE NUCLEOTIDE DERIVATIVES | MERRELL DOW PHARMA (US) | 1989-10-25 | — | — | CN | disclosed |
| EP-0335770-A2 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-10-04 | — | — | EP | disclosed |