Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763440 | 0.80 | POLB (0.48) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16249905 | 0.80 | POLB (0.52) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16249880 | 0.78 | POLB (0.50) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13784510 | 0.74 | POLB (0.43) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7825715 | 0.73 | POLB (0.41) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13867214 | 0.73 | GRM2 (0.44) | POLBTDP1ALDH1A1SLC1A2GRM2 | |
| SCHEMBL29143206 | 0.73 | POLB (0.41) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL18177762 | 0.72 | POLB (0.38) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16249737 | 0.72 | POLB (0.50) | POLBTDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29426398 | 0.72 | POLB (0.50) | POLBTDP1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094989-A1 | 5-HT RECEPTOR MODULATING COMPOUNDS | SERODUS AS (NO) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094989-A1 | 5-HT RECEPTOR MODULATING COMPOUNDS | HTR5A, HTR1A, HTR2A | POLB 4450/4885TDP1 3973/4885ALDH1A1 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.