Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 5/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180446 | 0.93 | STING1 (0.42) | STING1DHFRRXFP1POLB | |
| SCHEMBL23610456 | 0.93 | STING1 (0.42) | STING1DHFRRXFP1POLB | |
| SCHEMBL20221815 | 0.83 | PDE4D (0.33) | STING1 | |
| SCHEMBL20221827 | 0.83 | PDE4D (0.33) | STING1 | |
| SCHEMBL20180458 | 0.81 | DHFR (0.58) | DHFR | |
| SCHEMBL20180461 | 0.81 | DHFR (0.58) | DHFR | |
| SCHEMBL20180389 | 0.81 | DHFR (0.58) | DHFR | |
| SCHEMBL20180532 | 0.81 | DHFR (0.58) | DHFR | |
| SCHEMBL23621017 | 0.81 | DHFR (0.58) | DHFR | |
| SCHEMBL20180392 | 0.81 | DHFR (0.58) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730748-B2 | Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases | MSD INTERNATIONAL GMBH (CH) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730748-B2 | Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases | SLC10A1, PNP, PYGL | STING1 1665/4885DHFR 597/4885RXFP1 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.