Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738185 | 0.81 | HSD11B1 (0.47) | SMN1; SMN2HSD11B1HRH3ACHECHRM5 | |
| SCHEMBL22793920 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD11B1HRH3ACHEEPHX1 | |
| SCHEMBL2759515 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2HSD11B1HRH3ACHECHRM5 | |
| SCHEMBL11826729 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1HRH3ACHECHRM5 | |
| SCHEMBL20970530 | 0.73 | EBP (0.41) | ACHECHRM5ADRA2CKDM4EALDH1A1 | |
| SCHEMBL6672852 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1HRH3ACHECHRM5 | |
| SCHEMBL21440443 | 0.72 | NCF1 (0.48) | HRH3ACHEKDM4EALDH1A1 | |
| SCHEMBL4550260 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2HSD11B1KDM4EKMT2A | |
| SCHEMBL27267481 | 0.72 | NCF1 (0.48) | SMN1; SMN2HRH3ACHEEPHX1EPHX2 | |
| SCHEMBL26480956 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2HSD11B1HRH3EPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | disclosed |