Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22793920 | 0.91 | SMN1; SMN2 (0.46) | NCF1SMN1; SMN2HRH3ACHEEPHX1 | |
| SCHEMBL27269253 | 0.90 | NCF1 (0.43) | NCF1GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL27267485 | 0.87 | SMN1; SMN2 (0.38) | NCF1GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL27267891 | 0.86 | NCF1 (0.48) | NCF1GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL757866 | 0.85 | NCF1 (0.62) | NCF1GNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL23806855 | 0.84 | DRD2 (0.43) | GNAI3GNAO1GNAI1SMN1; SMN2HRH3 | |
| SCHEMBL24334496 | 0.83 | NCF1 (0.45) | NCF1GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL7738185 | 0.82 | HSD11B1 (0.47) | SMN1; SMN2HRH3ACHEEPHX1EPHX2 | |
| SCHEMBL26480956 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2HRH3EPHX1EPHX2 | |
| SCHEMBL13462652 | 0.81 | GNAI3 (0.59) | NCF1GNAI3GNAO1GNAI1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |