SCHEMBL26023329

SCHEMBL26023329

c1ncc2c(n1)CCSCC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30870718 0.86 TNKS2 (0.46) TNKS2
SCHEMBL7196077 0.86 TNKS2 (0.36) TNKS2
SCHEMBL9537255 0.86 TNKS2 (0.46) TNKS2
SCHEMBL9536810 0.80
SCHEMBL3380332 0.78
SCHEMBL35277 0.76
SCHEMBL29460883 0.76 SIGMAR1 (0.43)
SCHEMBL29438246 0.76
SCHEMBL19450166 0.74 SIGMAR1 (0.41)
SCHEMBL19450091 0.74 SIGMAR1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116861-A1 ANTI-DLL3 ANTIBODY AND PHARMACEUTICAL USE THEREOF, AND ANTIBODY-DRUG CONJUGATE CONTAINING ANTI-DLL3 ANTIBODY 江苏恒瑞医药股份有限公司 2023-06-29 WO disclosed