⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438246 | 1.00 | — | — | |
| SCHEMBL556889 | 0.95 | SIGMAR1 (0.43) | — | |
| SCHEMBL29460883 | 0.95 | SIGMAR1 (0.43) | — | |
| SCHEMBL2940094 | 0.93 | SIGMAR1 (0.41) | — | |
| SCHEMBL3988316 | 0.93 | SIGMAR1 (0.41) | — | |
| SCHEMBL3987657 | 0.93 | SIGMAR1 (0.41) | — | |
| SCHEMBL19450091 | 0.93 | SIGMAR1 (0.41) | — | |
| SCHEMBL2946238 | 0.93 | SIGMAR1 (0.41) | — | |
| SCHEMBL19450166 | 0.93 | SIGMAR1 (0.41) | — | |
| SCHEMBL9536810 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434247-B1 | Substituted furanopyrimidine compounds as PDE1 inhibitors | DART NEUROSCIENCE LLC (US) | 2022-09-06 | — | — | US | claimed |
| EP-3717488-B1 | SUBSTITUTED FURANOPYRIMIDINE COMPOUNDS AS PDE1 INHIBITORS | DART NEUROSCIENCE LLC (US) | 2021-09-29 | — | — | EP | claimed |
| US-11117887-B2 | Aryl substituted pyrimidines for use in influenza virus infection | Janssen Sciences Ireland Unlimited Company (IE) | 2021-09-14 | — | — | US | claimed |
| EP-3717488-A1 | SUBSTITUTED FURANOPYRIMIDINE COMPOUNDS AS PDE1 INHIBITORS | Dart NeuroScience, LLC (US) | 2020-10-07 | — | — | EP | claimed |
| CN-111655695-A | Substituted furopyrimidines as PDE1 inhibitors | 达特神经科学有限公司 | 2020-09-11 | — | — | CN | claimed |
| WO-2019104285-A1 | SUBSTITUTED FURANOPYRIMIDINE COMPOUNDS AS PDE1 INHIBITORS | DART NEUROSCIENCE, LLC (US) | 2019-05-31 | — | — | WO | claimed |
| US-20120035190-A1 | E-type Phenyl Acrylic Ester Compounds Containing Substituted Anilino Pyrimidine Group and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2012-02-09 | — | — | US | claimed |
| US-20110201628-A1 | HETEROCYCLIC JAK KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2011-08-18 | — | — | US | claimed |
| CN-1845907-B | Guanidine derivatives | ACTELION PHARMACEUTICALS LTD | 2010-07-28 | — | — | CN | claimed |
| US-7544691-B2 | Guanidine derivatives | ACTELION PHARMACEUTICALS, LTD. (CH) | 2009-06-09 | — | — | US | claimed |
| EP-1663993-B1 | GUANIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-03-12 | — | — | EP | claimed |
| US-20070123510-A1 | Guanidine derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2007-05-31 | — | — | US | claimed |
| CN-1845907-A | Guanidine derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2006-10-11 | — | — | CN | claimed |
| EP-1299397-A1 | NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESS FOR PREPARING THE SAME | LG Life Sciences Ltd. (KR) | 2003-04-09 | — | — | EP | claimed |
| WO-2002004464-A1 | NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESS FOR PREPARING THE SAME | LG LIFE SCIENCES LTD (KR) | 2002-01-17 | — | — | WO | claimed |
| EP-0530579-B1 | Condensed pyrimidine derivatives antitumor agents | EISAI CO LTD (JP) | 1998-11-11 | — | — | EP | claimed |
| US-5688800-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1997-11-18 | — | — | US | claimed |
| EP-0530579-A1 | Condensed pyrimidine derivatives antitumor agents | Eisai Co., Ltd. (JP) | 1993-03-10 | — | — | EP | claimed |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | LG CHEM, LTD. (KR) | 2026-05-26 | — | — | US | disclosed |
| EP-0057440-B1 | AMINOPYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND FUNGICIDAL, INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1985-05-22 | — | — | EP | disclosed |