Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553442 | 0.89 | ALDH1A1 (0.48) | PKMKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26028993 | 0.89 | HPGD (0.39) | PKMKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26029034 | 0.89 | HPGD (0.39) | PKMKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26029033 | 0.89 | HPGD (0.39) | PKMKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL25362119 | 0.86 | SMN1; SMN2 (0.44) | PKMKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL25364405 | 0.85 | NPC1 (0.58) | PKMALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL26025709 | 0.81 | PKM (0.50) | PKMKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26025892 | 0.79 | TSHR (0.38) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL25362146 | 0.79 | NPC1 (0.46) | ALDH1A1SMN1; SMN2L3MBTL1GAAPOLB | |
| SCHEMBL25363508 | 0.78 | SMN1; SMN2 (0.38) | KDM4EALDH1A1SMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154499-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-17 | — | — | WO | disclosed |