Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598131 | 0.79 | USP5 (0.44) | CDK4CDK6HTR6CDK2 | |
| SCHEMBL19092140 | 0.79 | CYP17A1 (0.33) | SCN9ASCN10ACYP17A1CYP1A2CDK4 | |
| SCHEMBL4126308 | 0.71 | MAPT (0.50) | CYP17A1CYP1A2CYP11B1CYP11B2NR3C1 | |
| SCHEMBL27837486 | 0.68 | CYP1A2 (0.39) | SCN9ACYP17A1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL441028 | 0.68 | CYP1A2 (0.54) | CYP17A1CYP1A2NR3C1 | |
| SCHEMBL20627070 | 0.67 | LMNA (0.40) | CYP1A2HTR6CYP3A4CYP2D6 | |
| SCHEMBL28772690 | 0.66 | CCR1 (0.38) | CYP17A1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL4112054 | 0.64 | SCN9A (0.41) | SCN9ACYP17A1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL17582162 | 0.64 | NPC1 (0.50) | SCN9ASCN10ACYP17A1CYP1A2NR3C1 | |
| SCHEMBL441916 | 0.62 | CCR1 (0.46) | SCN9ACYP17A1CYP1A2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219689-A2 | IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY | Novartis AG (CH) | 2023-08-02 | — | — | EP | disclosed |