Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627361 | 0.78 | MAOB (0.36) | LMNAHTR7KDM1AMAOAMAOB | |
| SCHEMBL21613703 | 0.75 | KDM4E (0.41) | LMNAL3MBTL3CYP2D6CYP2C19 | |
| SCHEMBL20627170 | 0.73 | LDHA (0.33) | L3MBTL3 | |
| SCHEMBL21448003 | 0.72 | L3MBTL3 (0.44) | L3MBTL3NPY1RHTR2AHTR2CHTR2B | |
| SCHEMBL20627169 | 0.70 | L3MBTL1 (0.46) | L3MBTL3CYP2D6CYP2C19 | |
| SCHEMBL18059725 | 0.69 | LMNA (0.36) | LMNAHTR7MAOAMAOBCYP1A2 | |
| SCHEMBL15916768 | 0.67 | EPHX2 (0.52) | LMNAHTR2AHTR2CHTR6CYP3A4 | |
| Hydrogen Sulfide SCHEMBL21089111 | 0.66 | NPY1R (0.39) | LMNAL3MBTL3NPY1RHTR2AHTR2C | |
| SCHEMBL13708519 | 0.65 | HTR2A (0.45) | HTR2AHTR2C | |
| SCHEMBL21447979 | 0.64 | L3MBTL3 (0.52) | LMNAL3MBTL3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070085-B1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-09 | — | — | EP | disclosed |