SCHEMBL26029124

SCHEMBL26029124

COCC(C)c1ccccc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
ADRA2B P18089 1/20 0.39
PTGS1 P23219 1/20 0.39
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 1/20 0.36
TSHR P16473 1/20 0.35
CYP3A4 P08684 3/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TAAR1 Q96RJ0 2/20 0.33
MAPT P10636 2/20 0.33
MCHR1 Q99705 1/20 0.33
CFTR P13569 1/20 0.33
HSD17B10 Q99714 1/20 0.33
DHFR P00374 2/20 0.32
DCPS Q96C86 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28762361 0.85 CD44 (0.38) ALDH1A1TDP1ADRA2BPTGS1CYP1A2
SCHEMBL28382868 0.82 ALDH1A1 (0.38) ALDH1A1TDP1ADRA2BPTGS1CYP1A2
SCHEMBL27412041 0.78 CA1 (0.48) ALDH1A1TDP1ADRA2BPTGS1CYP1A2
SCHEMBL27411561 0.78 CA1 (0.48) ALDH1A1TDP1ADRA2BPTGS1CYP1A2
SCHEMBL7868990 0.77 TAAR1 (0.52) ALDH1A1TDP1ADRA2BPTGS1TSHR
SCHEMBL111291 0.77 TSHR (0.59) ALDH1A1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL3820403 0.77 TSHR (0.59) ALDH1A1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL22969912 0.76 ADRB2 (0.43) ALDH1A1CYP1A2TSHRCYP3A4CASP1
SCHEMBL2118316 0.76 TSHR (0.35) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL25986475 0.75 ALDH1A1 (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158802-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF FULL-LIFE TECHNOLOGIES U.S. INC. (US) 2023-08-24 WO disclosed