Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 13/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363568 | 0.89 | CYP19A1 (0.43) | TRPV4TRPM8CYP19A1HSD11B1CYP3A4 | |
| SCHEMBL26025566 | 0.83 | TRPV4 (0.43) | TRPV4TRPM8ALKCYP19A1HSD11B1 | |
| SCHEMBL26025706 | 0.83 | HPGD (0.49) | HSD11B1CYP3A4MEN1KMT2A | |
| SCHEMBL3333148 | 0.81 | TSHR (0.50) | TRPV4TRPM8CYP19A1CYP3A4KCNH2 | |
| SCHEMBL26025712 | 0.78 | HPGD (0.37) | ALKHSD11B1IRAK4CYP3A4MEN1 | |
| SCHEMBL26027687 | 0.78 | HPGD (0.37) | ALKHSD11B1IRAK4CYP3A4MEN1 | |
| SCHEMBL26027684 | 0.78 | HPGD (0.37) | ALKHSD11B1IRAK4CYP3A4MEN1 | |
| SCHEMBL26028271 | 0.78 | GAA (0.39) | HSD11B1 | |
| SCHEMBL26029369 | 0.76 | SMN1; SMN2 (0.44) | IRAK4MEN1KMT2A | |
| SCHEMBL26029381 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154499-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-17 | — | — | WO | disclosed |