Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 6/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363527 | 0.89 | ATM (0.37) | GAATSHRPKMHSD11B1CCR1 | |
| SCHEMBL30540005 | 0.89 | ATM (0.37) | GAATSHRPKMHSD11B1CCR1 | |
| SCHEMBL26029369 | 0.81 | SMN1; SMN2 (0.44) | GAATSHRHPGDATML3MBTL1 | |
| SCHEMBL30540014 | 0.79 | KMT2A (0.36) | TSHRCCR1HDAC4L3MBTL1 | |
| SCHEMBL25363210 | 0.79 | KMT2A (0.36) | TSHRCCR1HDAC4L3MBTL1 | |
| SCHEMBL26025706 | 0.78 | HPGD (0.49) | GAAHSD11B1HPGDATML3MBTL1 | |
| SCHEMBL26029337 | 0.78 | TRPV4 (0.43) | HSD11B1 | |
| SCHEMBL31554872 | 0.77 | ATM (0.37) | GAATSHRPKMHSD11B1CCR1 | |
| SCHEMBL26029381 | 0.77 | ALDH1A1 (0.42) | TSHRHPGDATM | |
| SCHEMBL26025709 | 0.76 | PKM (0.50) | GAAPKML3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154499-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-17 | — | — | WO | disclosed |