SCHEMBL26032089

SCHEMBL26032089

CCCCCCCCCCCCCCCC(=O)NCCOCCNC(=O)CCOCCNC(=O)CC[C@H](NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCn1cc(C(C)C)nn1)C(=O)NCCOCCC(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.53
LPAR3 Q9UBY5 4/20 0.37
TLR2 O60603 2/20 0.37
LPAR1 Q92633 2/20 0.36
CCKAR P32238 1/20 0.36
CCKBR P32239 1/20 0.36
NOD1 Q9Y239 1/20 0.36
SIRT2 Q8IXJ6 2/20 0.36
FOLH1 Q04609 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032084 1.00 GLP1R (0.53) GLP1RLPAR3TLR2LPAR1CCKAR
SCHEMBL26032093 0.99 GLP1R (0.51) GLP1RLPAR3TLR2LPAR1NOD1
SCHEMBL26032229 0.89 GLP1R (0.39) GLP1RLPAR1
SCHEMBL26032116 0.81 HDAC1 (0.35) GLP1RLPAR1
SCHEMBL26032121 0.77 ZDHHC20 (0.36) GLP1R
SCHEMBL21087314 0.77 GLP1R (0.61) GLP1RFOLH1
SCHEMBL16921665 0.76 GLP1R (0.36) GLP1RTLR2FOLH1
SCHEMBL21087028 0.75 GLP1R (0.56) GLP1RFOLH1
SCHEMBL22923670 0.74 GLP1R (0.73) GLP1RLPAR3TLR2LPAR1NOD1
SCHEMBL26257845 0.74 GLP1R (0.64) GLP1RLPAR3TLR2LPAR1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885LPAR3 1763/4885TLR2 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.