SCHEMBL26032119

SCHEMBL26032119

CCCCCCCCCCCCCCCC(=O)NCCOCCNC(=O)CCOCCNC(=O)CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(=O)NCCOCCC(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC)C(=O)c1ccc(-c2nnc(SC(C)C)o2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.36
MAPT P10636 2/20 0.34
TP53 P04637 2/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CDC25A P30304 1/20 0.34
HSD17B10 Q99714 1/20 0.33
TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032132 0.97 POLB (0.36) POLBMAPTTP53TSHRALDH1A1
SCHEMBL26032111 0.89 HRH3 (0.40) MAPTTP53TSHRALDH1A1CDC25A
SCHEMBL26032130 0.88 DRD2 (0.36)
SCHEMBL26033618 0.87 DRD2 (0.36) POLB
SCHEMBL26033158 0.86 POLB (0.40) POLBMAPTTP53TSHRALDH1A1
SCHEMBL26032128 0.85 HPGD (0.36) POLBTSHRLMNANPSR1
SCHEMBL25835917 0.85 POLB (0.41) POLBMAPTTP53TSHRALDH1A1
SCHEMBL26032106 0.81 CNR2 (0.40) POLBMAPTTP53TSHR
SCHEMBL26032107 0.80 CNR1 (0.45) TSHRNPSR1
SCHEMBL25835923 0.77 POLB (0.33) POLBMAPTTP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 POLB 2117/4885MAPT 4094/4885TP53 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.