Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PIKFYVE | Q9Y2I7 | 11/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FES | P07332 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548872 | 0.84 | GAA (0.70) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL13548878 | 0.80 | LMNA (0.65) | GAAPIKFYVEKDM4EMAPTLMNA | |
| SCHEMBL26032125 | 0.79 | KDM5A (0.49) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL20363504 | 0.74 | GAA (0.62) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL4411464 | 0.74 | GAA (0.72) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL13548879 | 0.74 | KDM5A (0.74) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL4407764 | 0.73 | PIKFYVE (0.61) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL18827489 | 0.72 | GAA (0.72) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL14149070 | 0.70 | KDM5A (0.55) | GAAPIKFYVEKDM5AKDM4EMAPT | |
| SCHEMBL21135301 | 0.70 | PIKFYVE (0.69) | GAAPIKFYVEKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11714080-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-08-01 | — | — | US | disclosed |