Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | PIKFYVE | Q9Y2I7 | 10/20 | 0.59 |
| ▸ | FES | P07332 | 1/20 | 0.57 |
| ▸ | FER | P16591 | 1/20 | 0.57 |
| ▸ | TYK2 | P29597 | 1/20 | 0.57 |
| ▸ | FRK | P42685 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548880 | 0.87 | LMNA (0.60) | LMNAKDM4EMAPTHPGDPOLB | |
| SCHEMBL13548872 | 0.81 | GAA (0.70) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL26032126 | 0.80 | GAA (0.53) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL4407764 | 0.79 | PIKFYVE (0.61) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL18330253 | 0.79 | MAPT (1.00) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL429035 | 0.79 | MAPT (0.77) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL429036 | 0.79 | MAPT (0.77) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL21135301 | 0.79 | PIKFYVE (0.69) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL18121520 | 0.79 | PIKFYVE (0.73) | LMNAKDM4EMAPTHPGDPIKFYVE | |
| SCHEMBL18115250 | 0.79 | PIKFYVE (0.73) | LMNAKDM4EMAPTHPGDPIKFYVE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839617-B2 | Theramutein modulators | HMI Medical Innovations, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-11839617-B2 | Theramutein modulators | HMI Medical Innovations, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-11714080-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11692998-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-11692998-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210215671-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |
| US-20210215670-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |
| US-10955408-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2021-03-23 | — | — | US | disclosed |
| US-20210015825-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-01-21 | — | — | US | disclosed |
| US-20210008077-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-01-14 | — | — | US | disclosed |
| US-8367038-B2 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI Medical Innovations, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100016298-A1 | Theramutein modulators | HOUSEY GERAD M | 2010-01-21 | — | — | US | disclosed |
| US-20100016298-A1 | Theramutein modulators | HOUSEY GERAD M | 2010-01-21 | — | — | US | disclosed |
| US-20090275070-A1 | Compounds and Methods of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HOUSEY GERARD M | 2009-11-05 | — | — | US | disclosed |
| US-20090275070-A1 | Compounds and Methods of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HOUSEY GERARD M | 2009-11-05 | — | — | US | disclosed |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI MEDICAL INNOVATIONS, LLC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI MEDICAL INNOVATIONS, LLC. | 2008-10-30 | — | — | US | disclosed |
| WO-2008091681-A2 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-07-31 | — | — | WO | disclosed |
| US-20070111199-A1 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC | 2007-05-17 | — | — | US | disclosed |
| US-20070111199-A1 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008077-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | LMNA 2028/4885KDM4E 4221/4885MAPT 2984/4885 |
| US-20100016298-A1 | Theramutein modulators | TSG101, SERPINE1, PLAUR | LMNA 2028/4885KDM4E 4221/4885MAPT 2984/4885 |
| US-20210015825-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | LMNA 2028/4885KDM4E 4221/4885MAPT 2984/4885 |
| US-11839617-B2 | Theramutein modulators | TSG101, SERPINE1, PLAUR | LMNA 2028/4885KDM4E 4221/4885MAPT 2984/4885 |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | SERBP1, SERPINA6, UBE2V1 | LMNA 2128/4885KDM4E 4172/4885MAPT 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.