SCHEMBL582170

SCHEMBL582170

CCCCCCCCCCc1ccc2c(=O)c(O)c(-c3cc(O)c(O)c(O)c3)oc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.60
KMT2A Q03164 8/20 0.60
RECQL P46063 4/20 0.60
CD38 P28907 2/20 0.60
ABCC1 P33527 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
ABCB1 P08183 1/20 0.58
KDM4E B2RXH2 7/20 0.48
CYP3A4 P08684 7/20 0.48
MAPT P10636 7/20 0.48
HSD17B10 Q99714 7/20 0.48
CASP7 P55210 6/20 0.48
CASP1 P29466 5/20 0.48
TP53 P04637 5/20 0.48
ALDH1A1 P00352 5/20 0.48
HPGD P15428 5/20 0.48
ALOX15 P16050 5/20 0.48
MAPK1 P28482 4/20 0.48
CYP2C9 P11712 4/20 0.48
ALOX12 P18054 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13648970 1.00 MEN1 (0.60) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL12639915 1.00 MEN1 (0.60) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL4034075 1.00 MEN1 (0.60) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL4044129 1.00 MEN1 (0.60) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL4043879 1.00 MEN1 (0.60) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL4043863 1.00 MEN1 (0.60) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL4034126 0.95 MEN1 (0.62) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL2603350 0.91 CDK5 (0.61) MEN1KMT2ARECQLCD38ABCB1
SCHEMBL4035228 0.91 ABCB1 (0.58) MEN1KMT2ARECQLCD38ABCC1
SCHEMBL29633051 0.88 CYP3A4 (0.60) MEN1KMT2ATDP1ABCB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151508-A1 COMPOUNDS THE ROBERT GORDON UNIVERSITY 2010-06-17 US claimed
EP-2087350-A1 COMPOUNDS The Robert Gordon University (GB) 2009-08-12 EP claimed
WO-2008062184-A1 COMPOUNDS THE ROBERT GORDON UNIVERSITY (GB) 2008-05-29 WO claimed
US-8188144-B2 In vitro preservation of living animal cells and compounds suitable for use in the preservation of living animal cells ANTOXIS LIMITED (GB) 2012-05-29 US disclosed
US-8188144-B2 In vitro preservation of living animal cells and compounds suitable for use in the preservation of living animal cells ANTOXIS LIMITED (GB) 2012-05-29 US disclosed
US-20120094384-A1 USE OF COMPOUNDS FOR DIFFERENTIATION OF CELLS ANTOXIS LIMITED (GB) 2012-04-19 US disclosed
US-20120094384-A1 USE OF COMPOUNDS FOR DIFFERENTIATION OF CELLS ANTOXIS LIMITED (GB) 2012-04-19 US disclosed
US-20120094384-A1 USE OF COMPOUNDS FOR DIFFERENTIATION OF CELLS ANTOXIS LIMITED (GB) 2012-04-19 US disclosed
EP-2417250-A1 USE OF COMPOUNDS FOR DIFFERENTIATION OF CELLS Antoxis Limited (GB) 2012-02-15 EP disclosed
US-20100267132-A1 IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS ANTOXIS LIMITED (GB) 2010-10-21 US disclosed
US-20100267132-A1 IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS ANTOXIS LIMITED (GB) 2010-10-21 US disclosed
US-7601754-B2 Flavonoid compounds as therapeutic antioxidants ANTOXIS LIMITED (GB) 2009-10-13 US disclosed
US-7601754-B2 Flavonoid compounds as therapeutic antioxidants ANTOXIS LIMITED (GB) 2009-10-13 US disclosed
EP-2087350-A1 COMPOUNDS The Robert Gordon University (GB) 2009-08-12 EP disclosed
EP-2087350-A1 COMPOUNDS The Robert Gordon University (GB) 2009-08-12 EP disclosed
WO-2008062184-A1 COMPOUNDS THE ROBERT GORDON UNIVERSITY (GB) 2008-05-29 WO disclosed
WO-2008062184-A1 COMPOUNDS THE ROBERT GORDON UNIVERSITY (GB) 2008-05-29 WO disclosed
EP-1534698-B1 FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS ROWETT RES INST (GB) 2007-09-19 EP disclosed
EP-1534698-B1 FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS ROWETT RES INST (GB) 2007-09-19 EP disclosed
US-20060137207-A1 Flavonoid compounds as therapeutic antioxidants ANTOXIS LIMITED (GB) 2006-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267132-A1 IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS PIGS, AQP1, F12 MEN1 731/4885KMT2A 3131/4885RECQL 2229/4885
US-20100151508-A1 COMPOUNDS NFE2L2, RBBP4, GPX4 MEN1 4450/4885KMT2A 3816/4885RECQL 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.