Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709931 | 1.00 | SIGMAR1 (0.33) | SIGMAR1METAP1TSHRADH1BADH1A | |
| SCHEMBL21131756 | 0.87 | DNM1 (0.40) | SIGMAR1TSHRADH1BADH1AADH7 | |
| SCHEMBL9210510 | 0.81 | EPHX1 (0.41) | SIGMAR1TSHRADH1BADH1AADH7 | |
| SCHEMBL22960955 | 0.81 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL24722286 | 0.81 | METAP1 (0.33) | METAP1TSHR | |
| SCHEMBL19063319 | 0.81 | METAP1 (0.33) | METAP1TSHR | |
| SCHEMBL19846890 | 0.80 | SIGMAR1 (0.39) | SIGMAR1ADH1BADH1AADH7 | |
| SCHEMBL24080219 | 0.77 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL25111650 | 0.75 | METAP1 (0.39) | SIGMAR1METAP1 | |
| SCHEMBL21695543 | 0.75 | LMNA (0.33) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234550-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |