Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 2/20 | 0.58 |
| ▸ | SOD1 | P00441 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 4/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.48 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603461 | 0.90 | ABHD16A (0.57) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL14651901 | 0.89 | ABHD16A (0.64) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL14648817 | 0.85 | ABHD16A (0.60) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL2603436 | 0.84 | ABHD16A (0.61) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL2603471 | 0.84 | NR1I2 (0.52) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL15342888 | 0.83 | ABHD16A (0.75) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL14648822 | 0.83 | KARS1 (0.60) | POLA1NR1I2OPRK1CYP3A4MAPT | |
| SCHEMBL2603469 | 0.82 | ABHD16A (0.55) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL14651865 | 0.81 | ABHD16A (0.62) | ABHD16ASOD1POLA1NR1I2OPRK1 | |
| SCHEMBL15339329 | 0.81 | NR1H2 (0.52) | ABHD16ASOD1POLA1NR1I2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101250-A1 | NOVEL DEHYDROABIETIC ACID POLYMER | FUJIFILM CORPORATION (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101250-A1 | NOVEL DEHYDROABIETIC ACID POLYMER | DPAGT1, DDOST, ALAD | ABHD16A 73/4885SOD1 4636/4885POLA1 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.