Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290710 | 0.88 | TSHR (0.76) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL7298260 | 0.85 | ALDH1A1 (0.73) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL7300305 | 0.85 | TSHR (0.73) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL7300309 | 0.85 | TSHR (0.73) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL22986510 | 0.85 | TSHR (0.72) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL1938827 | 0.83 | ALDH1A1 (1.00) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL29766970 | 0.83 | ALDH1A1 (1.00) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL7298095 | 0.81 | TSHR (0.78) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL22986511 | 0.79 | TSHR (0.70) | TSHRCYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL7297642 | 0.78 | MAPT (0.73) | TSHRCYP3A4CYP2D6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730769-B2 | Compositions and methods for Williams Syndrome (WS) therapy | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730769-B2 | Compositions and methods for Williams Syndrome (WS) therapy | MAG, PMP22, WDR77 | TSHR 4488/4885CYP3A4 4885/4885CYP2D6 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.