Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984058 | 0.79 | LTA4H (0.49) | HRH3DRD3LTA4HMEN1KMT2A | |
| SCHEMBL6034272 | 0.72 | MEN1 (0.51) | HRH3DRD3LTA4HMEN1KMT2A | |
| SCHEMBL1251462 | 0.70 | KDM4E (0.55) | HRH3LTA4HMEN1KMT2AKDM4E | |
| SCHEMBL23640213 | 0.69 | MEN1 (0.58) | HRH3DRD3LTA4HMEN1KMT2A | |
| SCHEMBL26581441 | 0.69 | KDM4E (0.52) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL5217666 | 0.68 | LTA4H (0.62) | DRD3LTA4HMEN1KMT2AKDM4E | |
| SCHEMBL10176156 | 0.66 | MEN1 (0.55) | HRH3DRD3LTA4HMEN1KMT2A | |
| SCHEMBL6035058 | 0.66 | MEN1 (0.55) | HRH3DRD3LTA4HMEN1KMT2A | |
| SCHEMBL19541465 | 0.66 | MEN1 (0.58) | HRH3DRD3LTA4HMEN1KMT2A | |
| SCHEMBL12311929 | 0.65 | MEN1 (0.53) | HRH3DRD3LTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423435-B1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | UNIV VANDERBILT (US) | 2023-08-23 | — | — | EP | disclosed |