Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1251462 | 0.90 | KDM4E (0.55) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30983940 | 0.80 | GPR4 (0.49) | DRD3THRB | |
| SCHEMBL6034272 | 0.80 | MEN1 (0.51) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26037440 | 0.79 | HRH3 (0.41) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23640213 | 0.77 | MEN1 (0.58) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5217666 | 0.76 | LTA4H (0.62) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19541465 | 0.73 | MEN1 (0.58) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6035058 | 0.73 | MEN1 (0.55) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10176156 | 0.73 | MEN1 (0.55) | LTA4HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2254418 | 0.73 | MCL1 (0.41) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |