Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26039085 | 0.88 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL26039080 | 0.88 | ADORA2A (0.36) | DGAT1ADORA2AADORA2B | |
| SCHEMBL26039079 | 0.85 | ADORA2A (0.35) | DGAT1ADORA2AADORA2B | |
| SCHEMBL4312796 | 0.80 | DGAT1 (0.43) | DGAT1ADORA2AADORA2B | |
| SCHEMBL3300284 | 0.79 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL11976878 | 0.77 | DGAT1 (0.43) | DGAT1ADORA2AADORA2B | |
| SCHEMBL6525558 | 0.77 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL8889178 | 0.77 | ADORA2A (0.41) | DGAT1ADORA2AADORA2B | |
| SCHEMBL29300733 | 0.75 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL26046709 | 0.74 | PTGDR2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164358-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | WO | disclosed |
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | DGAT1 395/4885ADORA2A 995/4885ADORA2B 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.