Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25365631 | 0.81 | CA1 (0.49) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL31578554 | 0.81 | CA1 (0.49) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL24266210 | 0.74 | RORC (0.35) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL24265571 | 0.69 | MEN1 (0.39) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL10424045 | 0.68 | ALDH1A1 (0.58) | ATMCA1CA2CA12CA9 | |
| SCHEMBL10423590 | 0.68 | MEN1 (0.57) | ATMCA1CA2CA12CA9 | |
| SCHEMBL1585416 | 0.67 | MMP12 (0.37) | KDM4EHSD17B10KMT2AALOX5AP | |
| SCHEMBL20982482 | 0.67 | ALDH1A1 (0.50) | ATMCA1CA2CA12CA9 | |
| SCHEMBL26603188 | 0.66 | ALDH1A1 (0.49) | ATMCA1CA2CA12CA9 | |
| SCHEMBL16332477 | 0.65 | ATM (0.57) | ATMALDH1A1RAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159153-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-24 | — | — | WO | disclosed |