Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366898 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30520050 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30520106 | 0.84 | MAP4K4 (0.46) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25365761 | 0.84 | MAP4K4 (0.46) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30520125 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25365404 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25366229 | 0.80 | MAP4K4 (0.56) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30519914 | 0.80 | MAP4K4 (0.56) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25367687 | 0.80 | TGFBR1 (0.47) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30520035 | 0.80 | TGFBR1 (0.47) | ALDH1A1MAPTLMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |